Afoxolaner Generic Name: Naxolone (N-AFLOZ-uh-no)
Generic Brand Names: Afoxana, Amoxicillin, Azithromycin, Bactrim, Canine Distemper Vaccines, Canine Influenza Vaccines, Ciprofloxacin for Dogs, Doxycycline for Dogs, Erythromycin for Cats & Dogs/Canis familiaris Mixes With Cats And Dogs, Fosamax, Fluconazole For Dogs/Fluoroquinolones For Cats, Ibuprofen For Dogs/Ibuprofen Mixes With Cats & Dogs, Levofloxacin For Dogs/Levofloxacin Mixes With Cats & Dogs, Minocycline for Pets (Minocycline), Neomycin for Animals (Neomycin), Penicillins (Penicillin), Rifampin For Humans (Rifampin Mixes With Other Drugs), Sulfonamides (Sulfasalazine), Tetracyclines (Tetracaine)
Afoxolaner Generic Dosage For Dogs: 1 mg/kg per day or 0.5 mg/lb per day
The recommended dose of afoxolaner is 2 to 4 grams per pound of body weight. The dose should be divided into two separate daily doses.
The first dose should be given 24 hours after infection or contact with an infected tick. The second dose should be given 48 hours after the first dose. Treatment should be continued for one week after elimination of the tick. Injectable solution is given once a day, whereas tablets are given once a day for three days. Creon is given by mouth twice a day for 10 days.
Afoxolaner Generic Side Effects: anaphylaxis, congestion, diarrhea, dizziness, drowsiness, excitability, gas, headache, hives, indigestion, lack of energy, nausea, runny nose, skin rash
Afoxolaner Generic Precautions: This medication may cause drowsiness or dizziness. Do not drive or operate machinery until you know how this drug affects you.
Limit alcoholic beverages. Do not give within 2 hours before or after giving this medication.
Afoxolaner Generic Storage: Store this medication at room temperature and away from moisture and heat.
Afoxolaner Generic Instructions: Give this medication exactly as prescribed by your veterinarian.
Afoxolaner Generic Advise: Report any side effects to your doctor.
The information provided above is for informational purposes only and is not a substitute for medical advice. Always contact your vet if you have a medical concern.
Sources & references used in this article:
- Discovery and mode of action of afoxolaner, a new isoxazoline parasiticide for dogs (WL Shoop, EJ Hartline, BR Gould, ME Waddell… – Veterinary …, 2014 – Elsevier)
https://www.sciencedirect.com/science/article/pii/S0304401714000934 - The intravenous and oral pharmacokinetics of afoxolaner used as a monthly chewable antiparasitic for dogs (L Letendre, R Huang, V Kvaternick, J Harriman… – Veterinary …, 2014 – Elsevier)
https://www.sciencedirect.com/science/article/pii/S0304401714000946 - Assessment of afoxolaner efficacy against Otodectes cynotis infestations of dogs (D Carithers, J Crawford, C de Vos… – Parasites & …, 2016 – parasitesandvectors.biomedcentral …)
https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-016-1924-4 - Efficacy of afoxolaner in a clinical field study in dogs naturally infested with Sarcoptes scabiei (F Beugnet, C de Vos, J Liebenberg, L Halos, D Larsen… – Parasite, 2016 – ncbi.nlm.nih.gov)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912682/ - Efficacy of oral afoxolaner for the treatment of canine generalised demodicosis (F Beugnet, L Halos, D Larsen, C de Vos – Parasite, 2016 – ncbi.nlm.nih.gov)
https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4807374/ - Comparative speed of efficacy against Ctenocephalides felis of two oral treatments for dogs containing either afoxolaner or fluralaner (F Beugnet, J Liebenberg, L Halos – Veterinary Parasitology, 2015 – Elsevier)
https://www.sciencedirect.com/science/article/pii/S0304401714006281 - The ability of an oral formulation of afoxolaner to block the transmission of Babesia canis by Dermacentor reticulatus ticks to dogs (F Beugnet, L Halos, D Larsen, M Labuschagné… – Parasites & vectors, 2014 – Springer)
https://link.springer.com/article/10.1186/1756-3305-7-283